Here is the consummate text for anyone interested in learning how the cardiovascular system is regulated. Exercise and Circulation in Health and Disease is an expansive, broad-based reference that explores the functioning cardiovascular system from an integrative viewpoint.
This text includes both historical developments and recent findings on the diverse aspects of cardiovascular function. Exercise and Circulation in Health and Disease was inspired by the presentations of scientists from around the world at the Danish Academy of Science in Copenhagen and features the research and analysis of more than 40 internationally recognized authorities.
Exercise and Circulation in Health and Disease provides a conceptual framework for understanding cardiovascular function in health, as well as analysis of altered cardiovascular control during illness or under various physical and environmental conditions. Topics are presented from a basic science perspective with relevant implications for clinical and applied settings offered.
This valuable handbook for cardiovascular regulation reveals fundamental concepts as well as study models and techniques used to uncover regulatory mechanisms. It also serves as an encyclopedia of the functioning cardiovascular system from an integrative viewpoint and can be used as a reference guide and conceptual blueprint.
Part I introduces the subject of cardiovascular control mechanisms during exercise. In Part II, the text moves into specific implications for regional blood flow and oxygen delivery during exercise. Part III explores how external environmental conditions and internal biological factors affect cardiovascular regulation. Finally, Part IV examines cardiovascular regulation in disease.
Capturing both the complexity and order of cardiovascular function, Exercise and Circulation in Health and Disease covers the intricate mechanisms of cardiovascular regulation from an integrated point of view.
Additional Information
Preface
Introduction
Part I. Cardiovascular Control Mechanisms During Exercise
Chapter 1. Baroreceptor-Mediated Reflex Regulation of Blood Pressure During Exercise
Peter B. Raven, Jeffrey Potts, Xiangrong Shi, and James Pawelczyk
Chapter 2. The Exercise Pressor Reflex: Afferent Mechanisms, Medullary Sites, and Efferent Sympathetic Responses
Jeffrey T. Potts, Lawrence I. Sinoway, and Jere H. Mitchell
Chapter 3. The Cardiopulmonary Baroreflex
Chester A. Ray and Mitsuru Saito
Chapter 4. Control of Circulation and Respiration During Exercise: Central Neural Integration
Tony G. Waldrop and Jeffrey Kramer
Part II. Regional Blood Flow/Oxygen Delivery During Exercise
Chapter 5. Coronary Blood Flow and Cardiac Hemodynamics
Lennart Kaijser and Inge-Lis Kanstrup
Chapter 6. Pulmonary Circulation
John B. West and Odile Mathieu-Costello
Chapter 7. Liver, Spleen, and Kidneys
Inge-Lis Kanstrup
Chapter 8. Neural Control of Skin Circulation
Susanne F. Vissing
Chapter 9. Cerebral Blood Flow and Metabolism
Lisbeth G. Jørgensen, Markus Nowak, Kojiro Ide, and Niels H. Secher
Chapter 10. Muscle Blood Flow and Its Regulation
Bengt Saltin, Göran Rådegran, Maria Koskolou, Robert Roach, and Janice M. Marshall
Chapter 11. Dynamics of Microvascular Control in Skeletal Muscle
Steven S. Segal
Chapter 12. Integration of Muscle Blood Flow and Cardiac Output
Niels H. Secher, Atsuko Kagaya, and Bengt Saltin
Chapter 13. Oxygen Transport in Blood and to Mitochondria
John W. Severinghaus
Part III. Environmental Factors in Cardiovascular Regulation
Chapter 14. Cardiovascular Regulation During Hypoxia
Robert C. Roach
Chapter 15. Hyperbaric Pressure
Dag Linnarsson
Chapter 16. Microgravity
Gunnar Blomqvist
Chapter 17. Heat and Cold
Bodil Nielsen Johannsen
Chapter 18. Cardiovascular Regulation With Endurance Training
Robert Boushel, Peter Snell, and Bengt Saltin
Chapter 19. Aging: Can the Effects Be Prevented?
Frederick R. Cobb, Martin J. Sullivan, Michael B. Higginbotham, and Dalane Kitzman
Part IV. Cardiovascular Regulation in Disease
Chapter 20. Heart Failure
Lawrence I. Sinoway and Jere H. Mitchell
Chapter 21. Circulatory Regulation in Muscle Disease
Ronald G. Haller and John Vissing
Chapter 22. Peripheral Arterial Disease
Simon Green and Jesper Mehlsen
Chapter 23. Hypertension
Anthony F. Lever and Robert Boushel
Chapter 24. Orthostatic Stress and Autonomic Dysfunction
Johannes J. van Lieshout and Niels H. Secher
Contributors
Index
About the Editors
Developer / Author(s)
Editor(s)
Bengt Saltin, MD, PhD, is professor and director of the Copenhagen Muscle Research Centre. He has more than 30 years of cardiovascular research and teaching experience.
Dr. Saltin is a member of the Scandinavian Physiological Society, the American College of Sports Medicine (ACSM), and the Danish Academy of Sciences. He received citation and honor awards from the ACSM and was presented with the Novo Nordisk Award in 1999.
He has received Doctor Honoris Causa from the University of Paris, the University of Athens, the University of Guelph, the Aristotle University, the Norwegian University of Physical Education, and the University of Tartu.
Dr. Saltin obtained his medical degree from the Karolinska Institute in Stockholm. Dr. Saltin earned his PhD in Physiology at the Karolinska Institute in 1964.
Neils H. Secher, MD, PhD, is head of the Department of Anesthesia and the Abdominal Center at Rigshospitalet at the University of Copenhagen. A member of the Copenhagen Muscle Research Center, Dr. Secher began his work in cardiovascular research in 1972.
Dr. Secher is a member of the Scandinavian Physiological Society and the ACSM. He received a Young Investigators Award from the University of Copenhagen, where he earned his MD and PhD. He is associate editor of the European Journal of Applied Physiology. He is also a former world champion rower.
Jere Mitchell, MD, is Professor of Internal Medicine and Physiology at the University of Texas Southwestern Medical Center. A leading authority in the field of cardiovascular regulation, he has contributed to the basic scientific understanding of how the cardiovascular system is regulated during exercise.
Dr. Mitchell has published 350 papers in the field of cardiovascular regulation and has the distinction of having 40 years of consecutive National Institute of Health funding. His numerous honors include an Established Investigator award from the American Heart Association; Citation, Honor, and Joseph B. Wolffe Distinguished Lecturer awards from the ACSM; the Carl J. Wiggers Award from the Cardiovascular Section of the American Physiological Society; and the Young Investigators' Award and the Distinguished Scientist Award from the American College of Cardiology.
Dr. Mitchell received his medical degree from the University of Texas, Southwestern Medical School.
Robert Boushel, DSc, is a Research Fellow at the Institute for Sports Medicine Research at Bispebjerg Hospital in Copenhagen.
Dr. Boushel has served in the Division of Cardiology at the University of Texas Southwestern Medical Center, as a lecturer in cardiopulmonary science at Boston University, and as an associate professor/program coordinator in Exercise Sciences at New Hampshire Technical College.
He received his Dsc in Applied Anatomy and Physiology at Boston University and an MS in Exercise Science at the University of South Florida.